Differences

This shows you the differences between two versions of the page.

--- autonomics:antimuscarinics [2026/02/15 15:23] – [Core Physiologic Effects] andrew2393cns
+++ autonomics:antimuscarinics [2026/02/15 15:29] (current) – [Antimuscarinics / AntiCholinergics (Muscarinic Antagonists)] andrew2393cns
@@ Line 1: / Line 1: @@
-====== Antimuscarinics (Muscarinic Antagonists) ======
+====== Antimuscarinics / AntiCholinergics (Muscarinic Antagonists) ======
 Antimuscarinics block acetylcholine at muscarinic receptors and therefore inhibit parasympathetic activity.
@@ Line 6: / Line 6: @@
 <WRAP center round important 70%>
-Antimuscarinics = "Turn OFF rest-and-digest" and "Sympathetic-Like"
+Antimuscarinics = "Turn OFF rest-and-digest" → Sympathetic-like effects
 </WRAP>
@@ Line 48: / Line 48: @@
 ----
-===== Drug Groups =====
+===== Major Clinical Uses =====
-==== Respiratory (Inhaled) ====
+==== Bronchodilation ====
   * [[respiratory:antimuscarinics:ipratropium|Ipratropium]]
   * [[respiratory:antimuscarinics:tiotropium|Tiotropium]]
+  * [[respiratory:antimuscarinics:aclidinium|Aclidinium]]
+  * [[respiratory:antimuscarinics:umeclidinium|Umeclidinium]]
+  * [[respiratory:antimuscarinics:glycopyrrolate|Glycopyrrolate]]
+  * [[respiratory:antimuscarinics:revefenacin|Revefenacin]]
-==== Bladder Antispasmodics ====
+==== Overactive Bladder ====
-  * Oxybutynin
+  * [[gu:antimuscarinics:oxybutynin|Oxybutynin]]
-  * Tolterodine
+  * [[gu:antimuscarinics:tolterodine|Tolterodine]]
-  * Solifenacin
+  * [[gu:antimuscarinics:solifenacin|Solifenacin]]
+  * [[gu:antimuscarinics:darifenacin|Darifenacin]]
+  * [[gu:antimuscarinics:trospium|Trospium]]
-==== Ophthalmic ====
+==== GI Antispasmodic ====
-  * Atropine
+  * [[gi:antispasmodics:dicyclomine|Dicyclomine]]
-  * Tropicamide
+  * [[gi:antispasmodics:hyoscyamine|Hyoscyamine]]
-==== GI Antispasmodics ====
+==== Motion Sickness / CNS ====
-  * Dicyclomine
+  * [[cns:antimuscarinics:scopolamine|Scopolamine]]
-  * Hyoscyamine
+  * [[cns:antimuscarinics:benztropine|Benztropine]]
-==== CNS ====
+==== Ophthalmic Mydriasis ====
-  * Benztropine
+  * [[ophthalmology:antimuscarinics:atropine|Atropine]]
-  * Scopolamine
+  * [[ophthalmology:antimuscarinics:tropicamide|Tropicamide]]
+  * [[ophthalmology:antimuscarinics:cyclopentolate|Cyclopentolate]]
 ----
@@ Line 75: / Line 82: @@
 ===== Adverse Effects =====
-All antimuscarinics share the same predictable toxicity:
+All antimuscarinics share predictable toxicity:
   * Dry mouth
@@ Line 97: / Line 104: @@
 <WRAP round tip 90%>
-If a symptom involves excessive secretion or smooth muscle contraction → antimuscarinic drugs treat it.
+If a symptom involves excessive secretion or smooth muscle contraction → antimuscarinics treat it.
 </WRAP>
+Common real-world uses:
   * COPD bronchodilation
   * Overactive bladder
@@ Line 110: / Line 118: @@
   * [[respiratory:antimuscarinics:start|Respiratory Antimuscarinics]]
-  * GI antispasmodics
-  * Bladder antimuscarinics